研究方向

 

代表性论文

•  Liu X*, Wang S, Ma Q, Liang W, Li J, Zhu T, Li Q, Han Y*. A novel ITAM-containing immunoglobulin superfamily receptor involved in lamprey VLRB₊ lymphocyte immune response.Acta Biochim Biophys Sin (Shanghai). 2021，gmab035.
• Han Y, Li J, Pang Y, Xu L, Ma Q, Liu H, Song X, Su P, Sun F, Gou M, Lu J, Shan Y, Liu X*, Li Q*. Lamprey VLRB participates in pathogen detection, VLRB/L-BLNK/L-NF-κB (B-like cells) signal transduction, and development.Fish Shellfish Immunol. 2020, 105: 446-456.
• Li J, Liu H, Ma Q, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Guan H, Liu X*, Li Q*, Han Y*. VLRs expression were significantly affected by complement C3 knockdown morphants in Lampetra morii. Fish Shellfish Immunol. 2020,106:307-317.
• Li J, Ma Q, Liu H, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Liu X*, Li Q*, Han Y*. Complement component C1q plays a critical role in VLRA/VLRC-mediated immune response.Dev Comp Immunol. 2020,111:103750.
• Liang W, Gao M, Song X, Han Y, Go M, Su P, Li Q*, Liu X*. A novel CD81 homolog identified in lamprey, Lampetra japonica, with roles in the immune response of lamprey VLRB+ lymphocytes.Acta Biochim Biophys Sin (Shanghai). 2018,50(11):1158-1165.
• Shen Y, Zhang Y, Han Y, Su P, Gou M, Pang Y, Li Q*, Liu X*. A Novel Vav3 Homolog Identified in Lamprey, Lampetra japonica, with Roles in Lipopolysaccharide-Mediated Immune Response. Int J Mol Sci. 2017, 18(10):2035.
• Zhang X, Song X, Su P, Gou M, Wang H, Liu X*, Li Q*. Molecular cloning, expression pattern, and phylogenetic analysis of a tetraspanin CD82-like molecule in lamprey Lampetra japonica. Dev Genes Evol. 2016, 226(2):87-98.
• Zhang Q, Song X, Su P, Li R, Liu C, Gou M, Wang H, Liu X*, Li Q*. A novel homolog of protein tyrosine kinase Fyn identified in Lampetra japonica with roles in the immune response. Gene. 2016, 579(2): 193-200.
• Li R, Su P, Liu C, Zhang Q, Zhu T, Pang Y, Liu X*, Li Q*. A novel protein tyrosine kinase Tec identified in lamprey, Lampetra japonica. Acta Biochim Biophys Sin (Shanghai). 2015, 47(8):639-46.
• Liu C, Su P, Li R, Zhang Q, Zhu T, Liu X*, Li Q*. Molecular cloning, expression pattern, and molecular evolution of the spleen tyrosine kinase in lamprey, Lampetra japonica. Dev Genes Evol. 2015, 225(2):113-20.

 

开设课程

科研课题

• 《七鳃鳗NICIR 受体在VLR 介导的类淋巴细胞免疫应答跨膜信号转导中的作用研究》，LZ201783601，辽宁省教育厅基本科研重点项目，2017-2020
• 《基于比较转录组学的七鳃鳗类 T、B 淋巴细胞免疫应答信号传导分子机制》，31271323，国家自然科学基金，2013-2016