履历

• （2016）吉林大学博士
• （2010-2020）辽宁师范大学讲师
• （2021）辽宁师范大学助理副教授

研究方向

代表性论文

•  Guo SC, Yu B*, Jia Q, Yan HY, Wang LQ, Sun FF, Ma TH, Yang H*. Loureirin C extracted from Dracaena cochinchinensis S.C. Chen prevents rotaviral diarrhea in mice by inhibiting the intestinal Ca²⁺-activated Cl^- channels. J Ethnopharmacol, 10;318(Pt B):117077.
• Guo SC, Yan HY, Wang LQ, Liu Y, Yu B*. 2023. GlyH-101 and CaCC_inh-A01 Inhibited HT-29 Proliferation by Activating the Mitochondrial Apoptosis Pathway and Arresting the Cell Cycle. Anticancer Res, 43(8):3471-3477.
• Qu C, Guan X, Li Chang, Zhu XJ, Ma TH, Li HY*, Yu B*, Yang H*. 2023. Sesquiterpene lactones improve secretory diarrhea symptoms by inhibiting intestinal Ca²⁺-activated Cl^- channel activities directly and indirectly. Eur J Pharmacol, 15:955:175917.
• Wang H, Ma D, Zhu XJ, Liu PY, Li S, Yu B*, Yang H* .2021. Nimodipine inhibits intestinal and aortic smooth muscle contraction by regulating Ca²⁺-activated Cl^- channels. Toxicol Appl Pharmacol, 15:421:115543.
• Zhu XJ, Zhang WT, Jin LL, Zhang GP, Yang H*, Yu B* . 2020. Inhibitory activities of curzerenone, curdione, furanodienone, curcumol and germacrone on Ca²⁺-activated chloride channels. Fitoterapia, 147:104736.
• Yu B, Xie RF, Jin LL, Tian XG, Niu Y, Ma TH, Yang H*. 2019. trans-δ-Viniferin inhibits Ca²⁺-activated Cl^- channels and improves diarrhea symptoms. Fitoterapia, 139:104367.
• Yu B, Zhu XJ ,Yang XY ,Jin LL ,Xu J, Ma TH ,Yang H*.2019. Plumbagin Prevents Secretory Diarrhea by Inhibiting CaCC and CFTR Channel Activities. Front Pharmacol, 10:1181.
• Yu B, Jiang Y, Zhang B, Yang H*, Ma TH*. 2018. Resveratrol dimer trans-ε-viniferin prevents rotaviral diarrhea in mice by inhibition of the intestinal calcium-activated chloride channel. Pharmacol Res, 129:453-461.
• Yu B, Zhang GP, Jin LL, Zhang B, Yan D, Yang H*, Ye ZG*, Ma T. 2017. Inhibition of PAI-1 Activity by Toddalolactone as a Mechanism for Promoting Blood Circulation and Removing Stasis by Chinese Herb Zanthoxylum nitidum var. tomentosum. Front Pharmacol, 8:489.
• Yu B, Jiang Y, Jin LL, Ma TH*, Yang H*.2016. Role of Quercetin in Modulating Chloride Transport in the Intestine. Front Physiol, 7:549.
• Jiang Y^#, Yu B^#, Fang F, Cao HH, Ma TH, Yang H*. 2015. Modulation of chloride channel functions by the plant lignan compounds kobusin and eudesmin. Front Plant Sci, 6:1041.
• Yu B, Jiang Y, Liu Y, Ma TH*, Yang H*. 2015. Prevention of secretory diarrhea by ethanol extract from Bistortae rhizoma through inhibition of chloride channel. Bangladesh J Pharmacol, 10: 535-542.

开设课程

• 《人体解剖生理学》（本科生）/Human Anatomy and Physiology (For undergraduate)
• 《人体解剖生理学实验》（本科生）/Human Anatomy and Physiology Experiment (For undergraduate)
• 《细胞生物学实验》（本科生）/Experiment of Cell Biology (For undergraduate)
• 《生物制药技术》（本科生）/Bio-Pharmacy Technology(For undergraduate)
• 《生理学》（研究生）/ Physiology (For graduate)
• 《离子通道研究方法》（研究生）/ Methods for Studying Ion Channels (For graduate)
• 《科技论文写作与学术规范》（研究生）/ Scientific Writing and Academic Norms (For graduate)

• 科研课题

• 辽宁省教育厅项目（LJKMZ20221432）—肠上皮TMEM16A在胆汁酸诱导肝再生中的调控作用及机制研究，2022-2024，主持
• Study on the regulation and mechanism of intestinal epithelial TMEM16A in bile acid-induced liver regeneration. Education Department of Liaoning Province Project（LJKMZ20221432）.2022-2024. Principal Investigator.
• 辽宁省自然科学基金计划项目（博士启动）（2019-BS-155）—钙激活氯离子通道天然小分子抑制剂的发现及抗轮状病毒腹泻机制研究，2019-2021，主持
• Discovery of natural small molecule inhibitors of calcium activated chloride channels and the mechanism of anti-rotavirus diarrhea. Natural Science Foundation Project of Liaoning Province（2019-BS-155）. 2019-2021. Principal Investigator.
•  辽宁省教育厅项目（L201783646）—CFTR氯离子通道在腹泻主导型肠易激综合征病理机制中的作用研究，2017-2020，主持
• The role of CFTR chloride channel in the pathologic mechanism of diarrhoea-led irritable bowel syndrome. Education Department of Liaoning Province Project（L201783646）.2017-2020. Principal Investigator.

荣誉奖励

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